![]() The median age ranged from 59 to 70.5 years across cancer types. Patients were enrolled in matched trials of targeted agents affiliated with GI-SCREEN on the basis of genotyping results.Ī total of 11 gastrointestinal cancers were included, with colorectal cancer being the most common. Genotyping of tumor tissue samples from 5,743 patients with advanced gastrointestinal cancers enrolled in GI-SCREEN was centrally performed with NGS. ![]() SCRUM-Japan GI-SCREEN is a large-scale genomic profiling program in advanced gastrointestinal cancers using a validated genomic assay with the goal of facilitating enrollment in targeted clinical trials, generating real-world data, and performing clinicogenomic analysis for biomarker discovery. Genomic profiling programs have been implemented to apply next-generation sequencing (NGS) for facilitating trial enrollment.
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